publications 

The evolution of GLP-1s 

July 31, 2025

Prime's clinical experts share their perspectives on developing a holistic, individualized strategy to capitalize on opportunities and improve health outcomes. Our updated GLP-1 strategy brief offers new data and analysis on the long-term use, cost and clinical impact of GLP-1 therapies. The report includes real-world findings from our award-winning research on GLP-1 use for weight loss among commercially insured members. It also shares the latest drug pipeline, Prime’s evidence-based approach to GLP-1 management, and considerations for benefit design.​

Our report includes:

  • Real-world analysis over three years​
  • Pipeline, trend and spend​
  • Waste and misuse considerations​
  • Prime’s solutions, programs and strategies

Read the full GLP-1 strategy brief

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